Intraductal Ultrasound for High-Risk Patients: When Will the Last Be First?

When only the last one will do

An unknown positive number of items arrive at independent uniformly distributed times in the interval [0, 1] to a selector, whose task is to pick online the last one. We show that under the assumption of an adversary determining the number of items, there exists a game-theoretical equilibrium, in other words the selector and the adversary both possess optimal strategies. The probability of succ...

When will resistance be futile?

Cancer cells rapidly evolve a multitude of defense mechanisms to evade the effects of the oncologist's drug arsenal. Unfortunately, clinical strategies to overcome these lag far behind. This mismatch likely underlies our inability to implement new durable treatment strategies. Here, a new form of multidrug resistance, inducible drug glucuronidation, is discussed. This form was discovered while ...

[When will the nicotine vaccine be ready?].

And the First Shall Be the Last

This study analyzes the puzzle of Hungarian economic drifting in a long run perspective. The underlying puzzle for the investigation is why bad policies are invariably popular and good policies unpopular, thus why political and economic rationality never overlap. The first part of the article summarizes in eight points the basic features of the postwar period. Then six lessons are offered, whic...

Strategies of vaccine production against COVID-19: when will an effective vaccine be produced?

There is a strong consensus globally that production of an effective vaccine against SARS-CoV-2 is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. In this paper, we review vaccine candidate against COVID-19 and also cha...